Environmental Risk Factors Mesothelioma


1. About Middle skin

Chest organs such as lungs and heart, and abdominal organs such as gastrointestinal and liver are enveloped in membranes called pleural membrane, pericardium and peritoneum respectively, and the inner surface of the body is covered with these membranes. In this thin membrane, “mesothelial cells” line up.

2. What is mesothelioma

Environmental-Risk-Factors-Mesothelioma-Pic Environmental Risk Factors MesotheliomaCancer that develops from mesothelial cells is called “mesothelioma”. Depending on where it occurs, there are pleural mesothelioma, pericardial mesothelioma, peritoneal mesothelioma and so on.

Previously, it has been explained that mesothelioma is malignant and benign. Currently, however, mesothelioma means malignant tumor.

Cancers called pleural mesothelioma of benign tumors have changed their names to “sporadic fibrous tumors” and are not included in mesothelioma now. On the other hand, it is very rare for mesothelioma that develops in the peritoneum, but there are ones showing a benign course of “multiple cystic mesothelioma”.

Mesothelioma has a type that gets larger at one location (localized: Genkakushi) and a type that spreads throughout the membrane (diffuse). Many are spreading diffusely.


3. Symptom

In pleural mesothelioma, chest pain, cough, massive pleural effusion (S:

Dyspnea and chest compressions occur due to accumulation of liquid in the thoracic cavity. There are times when fever and weight loss of unexplained cause are seen.

In peritoneal mesothelioma, stomach is stretched by ascitic fluid (mucosa: liquid accumulates in the abdominal cavity).

Neither is a symptom characteristic of mesothelioma, it is difficult to detect early.

4. Epidemiology · Statistics

Environmental-Risk-Factors-Mesothelioma-Pic Environmental Risk Factors Mesothelioma

Mesothelioma occurs when most of it sucks asbestos (asbestos: cistern). Not only workers dealing with asbestos, but also family members of workers and residents around asbestos related factories occur. The more exposure to asbestos (exposure: gall bladder), the longer the period, the higher the risk of onset. It is more common in men than women. Some female patients may not be clearly related to asbestos. The period from sucking asbestos until mesothelioma occurs is very long and it is said to occur from about 25 years to 50 years (about 40 years on average).

If examined in detail, most mesothelioma patients have experienced exposure to asbestos in the past, but it is sometimes unclear, especially in women, whether they have been exposed to asbestos or not.

In addition, asbestos risk of lung cancer can be strengthened by smoking, but the risk of mesothelioma is considered not to be strengthened.

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